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Changelog

Source: NEWS.md

CanonicalTockySeq 0.1.0

  • Initial Public Release: Beta release of the CanonicalTockySeq framework for single-cell transcriptomic manifold analysis.
  • GradientTockySeq: Implementation of piecewise Spherical Linear Interpolation (SLERP) for geodesic trajectory reconstruction.
  • Conical Geometry: Introduction of the “Colimaçon” (Nautilus) coordinate system to decouple temporal progression from signaling intensity.
  • Tocky Integration: Full support for Nr4a3-Tocky Fluorescent Timer anchored landmark populations (New, Persistent, Arrested) in the tumour context.