Rapidly filters for genes that show significant variation along the
Gradient Tocky Time axis using a linear spline regression.
Automatically excludes cells with NA angles (Timer Negative).
Usage
SelectTockyGenes(expression_data, gradient_res, top_n = 2000, min_expr = 0.05)
Arguments
- expression_data
Sparse matrix or data frame (Genes x Cells).
- gradient_res
Either the data frame returned by GradientTocky_Slerp OR a named numeric vector of angles.
- top_n
Integer. Number of genes to return (default 2000).
- min_expr
Minimum proportion of cells expressing the gene (0-1). Default 0.05.
Value
A character vector of gene names sorted by dynamic score (R-squared).