Research

Introducing key publications and computational tools from the Ono lab. Find hidden magical creatures on this page!

primary research
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Tocky's Debut

The original report of Tocky from the Ono lab
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Decoding Foxp3 – From Treg Dogma to T-cell Dynamics

The second Tocky publication from the Ono Lab
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temporal trajectories elucidated by tocky

research paper reporting tockyDevelopment

review and opinion
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mechanism of retrovirus-induced leukaemia illuminated by tocky

The spectrum of self-reactive T cells and their activation mechanisms exploited by HTLV-1 infection
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decoding foxp3's code

introducing a new model for Foxp3 and Treg
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rethinking treg

the two controversies that matter

Computational Tools

Our Tocky software and general flow cytometry tools support analysis of Tocky data as well as broader flow cytometric datasets. The tools listed under General Flow Cytometric Tools are applicable to any flow cytometric data. Find a hidden magical Turtle (“Kame-san”) in this section!

Tocky
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TockyDevelopment

Multidimensional Tools for Flow Cytometric Fluorescent Timer Data
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TockyLocus

Quantitative Method for Fluorescent Timer Reporters
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TockyPrep

Data Preprocessing for Fluorescent Timer Reporters Using the Timer-Of-Cell-Kinetics-of-activitY (Tocky)

General Flow Cytometric Tools
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GatingTree

Pathfinding Analysis of Group-Specific Effects in Cytometry Data